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Graziano Joseph H.

E-mail: jg24@mail.cumc.columbia.edu

Joseph H. Graziano, Ph.D.

Professor of Environmental Health Sciences and Pharmacology
Associate Dean for Research
The Mailman School of Public Health at Columbia University
Director, The Columbia University Superfund Basic Research Program

Dr. Graziano has been a faculty member at the College of Physicians & Surgeons of Columbia University since 1979, and was Chairman of the Department of Environmental Health Sciences at the Mailman School of Public Health from 1991-2002, when he became Associate Dean for Research. Prior to that, he served on the faculties of The Rockefeller University and Cornell University Medical College. He was the founding director of Columbia University’s NIEHS Center for Environmental Health in Northern Manhattan. He is widely known as an expert on childhood lead poisoning, and his laboratory developed the drug (Succimer) that is now widely used to treat this condition. In addition, from 1983-1998, he was the principal investigator of a 15-year NIEHS-funded prospective study of childhood lead poisoning, carried out in the mining town of Kosovska Mitrovica, in the former Yugoslavia (now Serbia). In 2000, Dr. Graziano became the founding director of the Columbia University Superfund Basic Research Program (SBRP), entitled “Health Effects and Geochemistry of Arsenic and Lead”. The Columbia SBRP involves faculty from four schools of Columbia University, and includes geochemistry, hydrology and remediation research at four U.S. Superfund sites, as well as studies of arsenic metabolism and toxicity in families exposed to naturally occurring high concentrations of arsenic in drinking water in Bangladesh. His most recent research has discovered that both arsenic and manganese exposures are associated with cognitive deficits in children. His lab has also contributed to the recent findings from Bangladesh that folic acid facilitates arsenic methylation and elimination, leading to a decine in blood arsenic concentration.

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