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RAMAZZINI DAYS 2010
22-24 October 2010
Carpi, Italy
download program and abstracts

Schedule of Events

FRIDAY, 22 OCTOBER 2010

17:30

Meeting of the Executive Council (EC members only)
Hotel Touring

20:00

Welcome dinner
Ristorante B&B, Hotel Touring

SATURDAY, 23 OCTOBER 2010

9:00-12:15

Council of Fellows Statutory Session (Fellows only)
Town Hall of Carpi

12:30-13:45

Lunch
Ristorante B&B, Hotel Touring

SCIENTIFIC SESSION I: WORK OF THE FELLOWS
Chair: Melissa McDiarmid, USA and Carol Rice, USA
Sala delle Vedute, Palazzo dei Pio


14:00-15:00

ORAL COMMUNICATIONS part I

A Review And Update On Occupational Carcinogens
Kurt Straif, Germany/France download

Chromosome 5 & 7 Abnormalities In Oncology Personnel Handling Anti-Cancer Drugs
Melissia McDiarmid, USA download

Multicentre Mortality Study Of Polluted Sites Of National Concern In Italy - Sentieri Project
Pietro Comba, Italy download

Silica And Tuberculosis In A Globalising World - Forgotten But Not Gone
Rodney Ehrlich, South Africa
15:00-15:45 ATTENDED POSTER SESSION

Occupational Exposure to Particulates and Cardiovascular Disease
David Christiani, USA

Increased Oxidative Stress Levels In Chronic Liver Diseases Could Induce Cancerogenesis Through Mitochondrial Microsatellite Instability And Peroxidation Of The Repair Systems
Davide Degli Espositi, Italy/France [CR Fellow Morando Soffritti]

Validity And Reliability Of A Field Kit For Cholinesterase Estimation Amongst Workers Exposed To Organophosphate Insecticides
K Gardner, South Africa [CR Fellow Leslie London]

A Proposal For Calculating Occupational Exposure Limits For Organic Compounds On The Basis Of Their Physicochemical Properties
Marek Jakubowski, Poland

Do Terbutaline and Mold Associated Impairments of the Brain and Lung Relate to Autism?
Kaye Kilburn,USA

Medical Surveillance of Nanomaterials Workers
Steven Markowitz,USA

The Cell Phone Radiation Exposure Limit Certification Process Substantially Underestimates The Actual Exposure, Especially In Young Children
L. Lloyd Morgan,USA [CR Fellow Devra Davis]

Potential Markers of Activity of Pneumoconioses in Exhaled Breath Condensate and in Urine?
Daniela Pelclová,Czech Republic

Phthalate Exposure And Exposure Sources Among Pregnant Women In Jerusalem, Israel: Results Of A Pilot Study
Elihu Richter,Isreal

Cancer Risk Assessment, Primary Prevention And Chemoprevention In Occupational Health
Anna Tompa, Hungary

The Lead Industry and Public Health
Richard Wedeen,USA

A WBC-based Chromosomal Damage Among Chinese Benzene-Exposed Workers
Zhao-Lin Xia,China

Benzene Metabolite Hydroquinone And Leukemia. A Case Report
Ronald Zlotolow,USA [CR Fellow Nachman Brautbar]
15:45-16:30 ORAL COMMUNICATIONS part II

Controlling Pesticide Health And Environmental Hazards At Community Level in Lake Eyasi Basin, Karatu District, Tanzania
Vera Ngowi, Tanzania download

Wood Dust Exposure And Sinonasal Cancer: Studies On Tp53 Mutations And Inflammation-Related Mechanisms
Kirsti Husgafvel-Pursiainen, Finland

Metalworking Fluid Risks - Identified By Research Growing Out of A Union Campaign
Franklin Mirer, USA download
16:30-18:30

Free time

PRESENTATION OF THE RAMAZZINI AWARD AND RAMAZZINI LECTURE
Sala delle Vedute, Palazzo dei Pio


18:45-20:00

The 2010 Ramazzini Award will be conferred upon
Marja Sorsa, Finland download
who will deliver the 2010 Ramazzini lecture entitled:
"The 3 E's Principle in Public Health Research"
20:00 Social Dinner

SUNDAY, 24 OCTOBER 2010

SCIENTIFIC SESSION II:
"HORMONALLY ACTIVE CHEMICAL EXPOSURES: RECENT FINDINGS ON HALOGENATED HYDROCARBONS, RELEVANT CHILDHOOD EXPOSURES, AND ETHICS CONSIDERATIONS"

chairs: Mary Wolff (USA), Carl Cranor (USA)
Sala delle Vedute, Palazzo dei Pio

There are at least two generations of industrial chemicals having hormonal activity, mostly non-genotoxic. Old-age chemicals like DDT and dioxin continue to be of concern, with newly identified disorders and mechanisms of action. "Middle-aged", related POPs, have received attention recently, as well.

In addition, less persistent agents have emerged in commerce and in the environment in recent decades. Some of these latter chemicals are found at relatively high levels in the general population compared with reported exposures in the workplace, though such data are scarce. Meanwhile, occupational exposures to the POPs are no longer seen. The paradigm of environmental medicine, to examine the highest exposed persons to assess health effects, is thus challenged. Some bioactive chemicals, such as PCBs, DDT, and BPA, are reported at low levels (biomarkers < umolar) yet they continue to elicit concern.

Others exist at relatively high levels (>umolar). Examples of recently identified chemicals with reported biomarker levels in a range of known biological response include phthalates, perfluorocarboxylates, dichlorobenzene, and polybrominated diphenyl ethers; the last three in isolated geographical areas. While body burdens of DDT and dioxins have declined markedly over the past 4 decades, they are still detected in humans and research continues on endocrine-related health outcomes in relation to recent or long-past exposures.

Therefore an international perspective on these exposures will be informative in terms of exposures and plausible health concerns. Addressing knowledge gaps, such as possible overlap in occupational and general exposure intensity, would further elucidate dose-response relationships. Childhood exposures are of greatest concern. In addition, ethical considerations are now required in terms of informed consent, biomarker measurements, storage of specimens and data, and reporting back.


09:30

"Legally Poisoned: How The Law Put Us At Risk from Environmental Toxicants"
Carl Cranor, USA download
09:50 "Old-Age" Environmental Exposures: Delayed Effects From Past High-Level Exposures To POPs In A Fishing Community
Phillipe Grandjean, Denmark download
10:10 "Middle age": Examples Of High Exposures to Mixtures of Hormonally Active Chemicals And Health Effects [e.g. Pbde, pcbs, phthalates]
Henry Anderson, USA download
10:30 Coffee Break
10:45 "New-Age":Measuring Exposure Of Children And Their Mothers In Europe
Ludwine Casteleyn, Belgium download
11:05 Ethics And Data Protection In Human Biomarker Studies In Environmental Health
Karel Van Damme, Belgium download
11:25 - 12:15 Discussion
Moderator: Mary Wolff, USA and Carl Cranor, USA
12:15 Conference Closing
Phil Landrigan, USA
13:00

Farewell lunch
Ristorante B&B, Hotel Touring


 

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